Our no.10 misses out on the visit to Craven Cottage, as the Reds aim to recover from consecutive home defeats to Manchester City and Newcastle United.
Rashford travelled with the rest of the team but the Mancunian forward will not be involved in west London, due to injury.
Marcus took a heavy knock to his leg in training and was unable to finish the last session before the game.
The England international underwent a fitness test this morning, when it was decided he was unable to play.
Erik ten Hag has made six changes from the side which exited the Carabao Cup on Wednesday, with Aaron Wan-Bissaka making his first start for the club since early September after injury.