Ole Gunnar Solskjaer's side should have few fears of entering the Etihad Stadium, despite dropping more points in Wednesday's frustrating stalemate at Crystal Palace. After all, it's two wins out of two for the boss at the venue since taking charge, and history has shown that the Reds can often rise to the challenge of ending lengthy record-breaking streaks.
We decided to look at a few examples to provide some inspiration for Sunday afternoon's derby...
Arsenal (H) 2-0, 24 October 2004
Much was made of United's aggressive approach to the fixture, which stopped the Gunners reaching 50 unbeaten games in the Premier League, when they apparently had T-shirts prepared in order to acclaim the landmark.