Erik ten Hag's side will be looking to bounce back from the defeat at Newcastle on Saturday, and welcome Chelsea to Old Trafford on Wednesday before hosting Bournemouth three days later.
Some members of Marc Skinner's United Women will return after the international break, with the Reds facing a trip to Tottenham Hotspur in the Women's Super League.
Ahead of what is set to be a busy seven days at the club, here's our one-stop guide to everything that is happening this week...
MONDAY
As we look ahead to Wednesday's Premier League meeting with Chelsea, get the early team news from both camps.