Erik ten Hag's men will be bidding to reach round five of this season's Emirates FA Cup on Saturday evening, as we prepare to take on Reading at Old Trafford (20:00 GMT).
But before that, there's action for our Under-18s and Under-21s, while Marc Skinner's side are in Women's FA Cup action on Sunday afternoon.
So, we've put together a handy guide so that you are ready to follow all things United, over an action-packed few days of football ahead...
FRIDAY
Mark Dempsey's Under-21s are the first to take to the field, as they host Blackburn Rovers in the Premier League 2 later this evening, in a game that you can watch live on MUTV.