Included in it is Diogo Dalot, Leny Yoro and Joshua Zirkzee, who all took part in Tuesday morning's training session at Carrington following their respective recent absences.
Matthijs de Ligt was spotted going through an individual workout on another pitch and is one of only two first-team players to miss out through injury, with long-term absentee Lisandro Martinez being the other.
Young forward Chido Obi is ineligible for the Europa League.
TRAVELLING SQUAD
Goalkeepers Defenders Tyler Fredricson Midfielders Forwards Ruben Amorim is expected to speak about his squad and provide an update on the availability of his players for Wednesday's 20:00 BST kick-off during a pre-match press conference this (Tuesday) evening.
Altay Bayindir
Tom Heaton
Dermot Mee
Andre Onana
Harry Amass
Patrick Chinazaekpere Dorgu
Diogo Dalot
Ayden Heaven
Victor Lindelof
Harry Maguire
Noussair Mazraoui
Luke Shaw
Leny Yoro
Casemiro
Toby Collyer
Christian Eriksen
Bruno Fernandes
Kobbie Mainoo
Mason Mount
Manuel Ugarte
Amad
Alejandro Garnacho
Rasmus Hojlund
Joshua Zirkzee