It's been almost five years since we played Wolfsburg in our last meeting with a German outfit, but such head-to-heads have been commonplace in the Champions League era, with United's back catalogue versus Bundesliga opposition now stretching to 33 games, 17 of which have been wins.
Prior to the showdown with Julian Nagelsmann's highly rated charges, here are our top 10 victories - you may have some fond memories of these games...
10. UNITED 2 WOLFSBURG 1 (CHAMPIONS LEAGUE GROUP STAGE, 2015)
Our first-ever meeting with the Wolves, when they were champions of Germany in 2009, had seen us come from a goal down to win, and six years on, history repeated itself as we returned to the Champions League after a season-long hiatus.