Following games against both Everton and Reading in the two previous rounds at Old Trafford, Erik ten Hag's side will welcome the Hammers to M16 in the week commencing 27 February.
With a chance to book our place in the quarter-finals at stake, the Reds have now remarkably been drawn at home for the ninth consecutive time in domestic cup competitions, if you discount the Carabao Cup last-four draw being away as it was a two-legged tie anyway.
As away draws have been at a premium for United fans, here's a short trip down memory lane, at some of our best performances on the road in the FA Cup.