The Reds face Pep Guardiola's Blues in the 12:30 BST kick-off in our final match before the last international break of the year.
Ole is without Raphael Varane and Edinson Cavani for the big game but Victor Lindelof is available after missing the Atalanta tie in the Champions League in midweek.
There are three changes in total from the European clash in Bergamo, including Fred, who replaces the suspended Paul Pogba in midfield.
Marcus Rashford starts on the bench, with Mason Greenwood introduced after an impressive contribution as a substitute in Italy, while Lindelof is in for Varane after proving his fitness in time to play.