This is the second season in a row that Ole Gunnar Solskjaer’s side have faced a Spanish opponent in the competition and the Reds will be hoping for a better outcome on this occasion.
United were eliminated in the semi-finals of the tournament last season by Sevilla, meaning we haven’t won any of our last nine games against La Liga clubs.
Despite that, La Reales boss downplayed our recent record ahead of the clash.
“It was probably a very different Man United when they were knocked out by these Spanish teams in the past,” Alguacil said during Wednesday’s press conference.