Despite a long-standing rivalry between the two clubs, there have been a handful of players who have donned both red and white in their careers.
Ahead of the game, we’ve profiled the most famous names who have turned out for both teams in the last 50 years...
GORDON MCQUEEN Considered as the long-term successor to the ageing Jack Charlton by Don Revie, the big Scot formed a formidable defensive pairing with Norman Hunter in the mid-70s.
Leeds shelled out £30,000 to secure the signing of Gordon McQueen from St Mirren before the start of the 1972/73 season.