The boss faced the media at Carrington before flying out with his squad for Thursday's 17:45 BST kick-off in Cyprus.
After defenders Raphael Varane, Harry Maguire and Aaron Wan-Bissaka, plus midfielder Donny van de Beek, were missing from the morning's open training session at Carrington, their injury situation was one of the first topics posed to Erik during the briefing.
"They are unavailable for tomorrow," said Ten Hag of the aforementioned quartet.
"Yes, in the case of Rapha, I have good hope [that he comes back soon].
"Harry will take a little bit longer. The other two, I cannot give a prognosis.