The manager was asked about the 37-year-old throughout Friday's pre-match press conference at Carrington, ahead of Sunday's Premier League opener against Brighton & Hove Albion.
Some of the questioning focused on reports that Ronaldo had left Old Trafford prior to the end of last weekend's match with Rayo Vallecano, after being substituted at half-time.
In response, Ten Hag was keen to set the record straight.
“Now I have to point [out],” Ten Hag began, “there were many players who left, but the spotlight is on Cristiano and that's not right.
“That is what I said is not correct.