Senne Lammens makes his Reds debut, as he replaces Altay Bayindir in goal for the game at Old Trafford.
Leny Yoro returns to the backline, while Amad is back after missing the meeting with the Bees due to a family bereavement.
It looks as though the Ivorian will feature at right wing-back, with Diogo Dalot moving over to the left flank.
Casemiro partners captain Bruno Fernandes in midfield, after serving his one-match suspension, while there's a first start for Mason Mount since our victory over Burnley here in August.
Harry Maguire, Patrick Chinazaekpere Dorgu, Manuel Ugarte and Matheus Cunha all join Bayindir in making way, and have been named on the bench.