The boss must have carefully pondered his team for the all-important clash at San Mames in Bilbao, which kicks off at 20:00 BST.
There is good news regarding Leny Yoro, as the young Frenchman has recovered from the injury sustained in the home game against West Ham United recently. As a result, he takes his place in the three-man defence, probably alongside Harry Maguire and Luke Shaw.
It is possible Noussair Mazraoui could be at the back, which would mean Shaw operating on the left and Patrick Chinazaekpere Dorgu switching to the right.
Bruno Fernandes is tasked with starting in a deeper midfield position, alongside European competition past master Casemiro, who scored in both legs of the semi-final against this stadium's hosts Athletic Club.