The United boss is hoping he can mastermind another defeat of our neighbours, following wins against them this term, in the Champions League with former club Sporting, and thanks to the Etihad Stadium comeback triumph with the Reds in December.
Despite the disappointment of a 1-0 defeat at Nottingham Forest, in our first game after a long break, there was some positive news with the return to action of Leny Yoro, Harry Maguire and Mason Mount.
During his press conference at Carrington to preview Sunday's 16:30 BST kick-off, Amorim said he could welcome Kobbie Mainoo back into the matchday squad, after the young midfielder has been out, due to injury, since the Emirates FA Cup tie against Leicester City in February.