On one of the great European nights at Old Trafford in recent years, goals from Marcus Rashford, Harry Maguire and Cristiano Ronaldo capped an incredible turnaround against the Italians.
Another big game lies in wait on Sunday, this time in the Premier League against Jurgen Klopp's in-form Liverpool, and preparation is clearly key for United, who will have had 24 hours' less rest than the Merseysiders.
Our photographers snapped the players training at Carrington this morning, with last night's four substitutes Paul Pogba, Edinson Cavani, Jadon Sancho and Nemanja Matic all involved.
It was also encouraging to see French forward Anthony Martial take part in the session.