The Reds have only raised the curtain on our league season on a Monday twice before, with mixed fortunes, while a Friday-night start back in 2018/19 is the only other occasion when we've kicked off our campaign on a weekday.
But when Wolves visit Old Trafford on 14 August, for a 20:00 BST kick-off, the count will go up by one.
PREVIOUS MONDAY OPENERS
United 3 Newcastle 0 (16 August 2010)
Newcastle were the visitors to Old Trafford at the beginning of the 2010/11 season, and the Reds started what turned out to be a title-winning campaign in style.