The Old Trafford encounter marks a return to Premier League action for the Reds with a first fixture since the Champions League tie against Atletico Madrid on 15 March.
Following the players' international exertions, they are back training at Carrington in preparation for the test posed by the 10th-placed Foxes.
Speaking at his press conference at Carrington, the boss suggested that Edinson Cavani will be unavailable for at least the next couple of weeks. The striker reportedly suffered a calf problem which led to his withdrawal during the first half of Uruguay's World Cup qualifier against Chile.