Another game at Old Trafford provides valuable experience to lead coach Travis Binnion's side, who take on the Toffees in the 19:00 GMT kick-off, with the action live on MUTV.
Extra-time and penalties will come into effect, if required.
“Yes, it’s a great opportunity,” Ralf told MUTV's Mark Sullivan. “Before Christmas, I intended to watch one of those games but, due to COVID, it was not possible.
“It is a great opportunity to play in this famous stadium and hopefully they can win the game.”
The Under-18s reached this fifth-round stage with wins over Scunthorpe United, at the Theatre of Dreams, and away to Reading.