Erik ten Hag's side were held to a 1-1 draw with Burnley last time out, with just four league outings now remaining before our end-of-season clash with Manchester City at Wembley Stadium in the FA Cup final.
United have been dealt a further blow in the build-up to tonight's fixture, with both Harry Maguire and Marcus Rashford expected to miss out in the capital.
Our popular United Predictions game gives you, the supporter, a chance to forecast how you feel we will fare against the Eagles - and you only have a couple of hours left to do so.