The opposition that evening, 63 years ago, were European champions and eventual winners Real Madrid and, although the Spaniards raced into a two-goal lead, second-half strikes from Tommy Taylor and Bobby Charlton ensured the shares were spoiled on a thrilling night.
United have served up plenty more unforgettable evenings on home soil down the years. Here’s the rundown of our top 10...
10. UNITED 3 MILAN 2 (CHAMPIONS LEAGUE SEMI-FINAL, 2006/07)
A magical display from future Ballon d’Or winner Kaka had Sir Alex Ferguson’s side staring at a home defeat in this Champions League semi-final, before a Wayne Rooney double – the second in injury-time – sent Old Trafford rocking.