The Reds are flying high in Europe with three wins from four so far and currently top Group H, with PSG and German side RB Leipzig just behind in a close race for the knockout stages of the tournament.
The Reds will also be hoping to extend our winning run in all competitions which now stretches to four games.
Ahead of the huge European clash, we’re detailing all the need-to-know information.
ESSENTIAL INFO
Kick-off at Old Trafford will take place at 20:00 GMT on Wednesday and fans in the UK can watch the game live on BT Sport.