The 16:30 BST kick-off is sandwiched between our two key Europa League quarter-final ties against Lyon and, following the 2-2 draw in the first leg in France, clearly the timing of such a tough examination in the north east is not ideal.
The Magpies are chasing a place in next season's Champions League, with their current position of fifth enough to achieve that aim in 2025/26.
Here is everything you need to know ahead of the St James' Park encounter at the weekend...
HOW TO WATCH AND FOLLOW
The tussle on Tyneside is live on Sky Sports in the UK, kicking off at 16:30 BST, but you can also get exclusive build-up on MUTV from 15:25 BST.