Marcus Rashford was substituted in the second half of England's Euro 2024 qualifier against Malta moments after colliding with team-mate Trent Alexander-Arnold.
It is unclear how serious a knock the Manchester United forward picked up but he was immediately replaced by Chelsea's Cole Palmer.
It will be a potential worry for United boss Erik ten Hag, who is already without Lisandro Martinez, Luke Shaw, Casemiro, Christian Eriksen and Rasmus Hojlund.
The recent injury woes have only added to the problems at Old Trafford, with Ten Hag struggling to find any sort of consistency in terms of results.