Interim head coach Darren Fletcher makes three changes to our side that started Wednesday's Premier League draw with Burnley, for the third-round tie at home to the Seagulls.
Kobbie Mainoo and Mason Mount are two of the incomings, after returning from their recent injuries with substitute cameos in midweek, while Leny Yoro is also restored to the XI.
The trio replace Casemiro, Ayden Heaven and Luke Shaw, with Shaw not in the matchday squad this afternoon.
If Fletcher is to line us up in a four-man defence, as he did at Turf Moor, it could be Diogo Dalot, Yoro, Lisandro Martinez and Patrick Chinazaekpere Dorgu in front of Senne Lammens in goal.