The man in the middle will be a new face to most Reds supporters, as this is only his fifth Premier League assignment, after racking up lots of experience in the EFL, since 2021/22.
The Old Trafford encounter is his third top-flight outing this term, after overseeing Aston Villa's 2-1 win over Burnley and Chelsea's 3-0 victory at home to Wolverhampton Wanderers.
Kitchen, who hails from Durham in the north-east, was the fourth official for the Hammers' 2-0 loss to Liverpool at the London Stadium on Sunday.
Dan Cook and Ian Hussin will be his assistants, running the lines, with Michael Salisbury on fourth-official duties.