The Reds are currently unbeaten in the league phase of the competition, boasting three wins from three against Valerenga, Atletico de Madrid and Paris Saint-Germain so far.
Marc Skinner's side suffered defeat in the Manchester derby over the weekend, but bouncing back will be top of the to-do list as we head to Germany.
Want to follow along? Read on here to find out the latest on TV info, ticketing, team news and form guides...
HOW TO WATCH AND FOLLOW
Wednesday's clash at the Volkswagen Arena kicks off at 17:45 GMT and will be shown live in the UK on Disney+.