Erik ten Hag’s men come into this game off the back of an incredible comeback against Aston Villa at Old Trafford, where the Reds overturned a two-goal deficit to triumph 3-2 with a brace by Alejandro Garnacho and Rasmus Hojlund's dramatic first Premier League strike.
The hosts, meanwhile, won 3-1 away at Newcastle United and have a new manager on the touchline in the form of Nuno Espirito Santo, following Steve Cooper's dismissal.
Ahead of our trip to the City Ground, here are the key things you need to know…
HOW CAN I FOLLOW THE GAME?