The Hammers are the visitors to Old Trafford for a third-round tie this Wednesday, 22 September at 19:45 BST on the back of our thrilling away win in the Premier League at the weekend.
This time, the reward for a victory will be a place in the next round of a competition we have reached the semi-finals in for the last two seasons in a row.
Ahead of our first floodlit game at the Theatre of Dreams in 2021/22, here is everything you need to know…
HOW TO FOLLOW
There are a limited number of tickets still available for Wednesday evening’s match that can be purchased online from manutd.