Find out how each side is shaping up going into this fixture...
HOW TO WATCH
The game is set to be broadcast live on BT Sport 2 and Ultimate, with coverage commencing an hour before kick-off at 19:00 GMT.
Alternatively, you can keep up to date via the Manchester United App and on our website, where we will bring you the team news, and regular updates, as well as pre-match and post-match interviews.
TEAM NEWS
Edinson Cavani has missed both of United’s recent Premier League wins over Leeds and Brighton, and the Uruguayan remains a doubt for the trip to Madrid.