But what about the other seven ties being played at this stage of the competition? And who will win each one and join Arsenal, Fenerbahce, Ferencvaros, Feyenoord, Freiburg, Real Betis, Real Sociedad and Union Saint-Gilloise in going through to the last 16?
Here’s the lowdown on Thursday’s play-off first legs…
AJAX v UNION BERLIN (17:45 GMT)
Ajax were unlucky to come up against Napoli and Liverpool in their Champions League group and this is another tricky looking draw, with Union Berlin currently second in the Bundesliga, just one point behind reigning champions Bayern Munich.