Erik ten Hag's first European expedition as Reds boss will feature matches against Real Sociedad, Sheriff Tiraspol and Omonia Nicosia.
The group winners advance directly to the round of 16, while the runners-up meet the eight teams who finish third in the Champions League pools. Clubs finishing third transfer to the UEFA Conference League.
The Europa League final is to be staged in Budapest on Wednesday 31 May, 2023.
The Reds faced Real Sociedad last year in the Europa League but the away leg, a 4-0 victory, was held in Turin. The second leg finished goalless at Old Trafford.