The Reds will take on the Villans at the Theatre of Dreams at 12:30 GMT on Saturday 3 December and it will be broadcast live on Sky Sports in the UK.
Our clash with Villa was originally pencilled in for the Sunday of that weekend but has been moved forward just under 24 hours following the announcement of the latest TV picks.
Supporters can purchase tickets and hospitality packages for the game here.
The match will be United Women’s third at Old Trafford, after WSL fixtures against West Ham and Everton over the previous two seasons.