Different to the win over Sunderland before the recent international break are the inclusions of centre-back Harry Maguire and forward Matheus Cunha.
The pair come in to replace Leny Yoro and Benjamin Sesko, with Cunha a candidate to line up as our centre-forward in the 16:30 BST kick-off, should it be Amorim's favoured 3-4-2-1 system.
From the back, it's Senne Lammens in goal, with the summer signing keeping his place after an impressive debut and clean sheet against Sunderland at Old Trafford.
Harry Maguire is expected to slot into a back three alongside Matthijs de Ligt and Luke Shaw, and they could be flanked by Amad and Diogo Dalot as wing-backs.