The only change to the group that faced Celta Vigo last Friday is the inclusion of Lucas Ocampos, who was suspended for the 2-2 draw in La Liga.
The Argentina international takes the place of Senegalese midfielder Pape Gueye, who is not eligible to play in Europe for Jose Luis Mendilibar's side.
As per a statement on Sevilla’s official website, the other players who are unavailable are Joan Jordan and Tecatito Corona due to injury.
The 22-man travelling squad to face @ManUtd in the @EuropaLeague ud83dudcaa
— Sevilla FC (@SevillaFC_ENG) April 11, 2023
United defender Alex Telles is in Sevilla's 22-man squad after overcoming an injury he sustained during the World Cup.