The Uruguayan has been troubled by a tendon problem this term, which has kept him sidelined since the Champions League tie at Atalanta on 2 November.
It is not known if he will be available for the trip to London for Sunday's Premier League clash with top-of-the-table Chelsea at Stamford Bridge.
"During this period of the international break, I've had the chance to stop and focus on this niggling injury that I'm feeling in the tendon in my leg," he told club media at Carrington. "So I can speed up my recovery and come back quickly and be available for my club and national team.