Manchester United slipped to a slender 4-3 defeat on Sunday afternoon at Brentford, where Ruben Amorim fielded the youngest Premier League XI in the club's history.
With next Thursday's UEFA Europa League semi-final second leg against Athletic Club taking priority, Amorim made eight changes to the line-up from the first leg and the hosts eventually took advantage.
Mason Mount's 14th-minute opener - at the same ground where he scored in last season's 1-1 draw between the clubs - gave the travelling fans hope of an away win for the youthful team.
But an unfortunate own goal by Luke Shaw and a far-post header by Kevin Schade, with United defender Matthijs de Ligt injured in the build-up, put Brentford 2-1 up at the break.