The centre-back, who has worked his way back into the Reds' side of late for the games against Atalanta and Manchester City, missed the 3-0 win over Mozambique due to suspension.
However, he is part of a full squad at coach Patrick Beaumelle's disposal for the crunch clash away to Cameroon in Group D of the African section.
Bailly looks set to start at the heart of the defence as the Elephants must avoid defeat in order to remain top of the group, with Malawi and Mozambique out of the running.
Ivory Coast have 13 points, with Cameroon one behind, heading into the final fixture, which kicks off at 19:00 GMT in Yaounde.