The boss has made two changes to the team that was beaten 3-0 in last Sunday’s Manchester derby against City at the Etihad Stadium.
Harry Maguire, who made his 250th United appearance last time out, comes into the defence in place of Leny Yoro.
Casemiro returns in midfield to partner captain Bruno Fernandes as Manuel Ugarte, like Yoro, moves to the substitutes’ bench.
Also among the back-up brigade are fit-again pair Mason Mount - who could face his former club - and Matheus Cunha, after the attacking duo missed the derby through injury.
Altay Bayindir continues in goal, with new signing Semme Lammens on the bench, while Maguire is joined in the back three by Matthijs De Ligt and Luke Shaw.