The younger side, coached by Adam Lawrence, will travel to Sunderland for a Premier League U18 North game that will be shown live on MUTV, ManUtd.com and the United App.
Kick-off at the Academy of Light is scheduled for 12:30 BST, with our club media's coverage beginning 15 minutes beforehand.
Meanwhile, United's Under-21s are at home to Arsenal in Premier League 2; however, fans will be unable to attend on this occasion, as the fixture is being played behind closed doors at Carrington.
The game will get under way at 12:00 BST and while it will not be broadcast live, match highlights will be available on MUTV, ManUtd.