Liverpool, Manchester City, Manchester United and Chelsea are among the hardest hit after 10 Premier League stars from South America were banned from playing this weekend - despite them skipping the international break to stay in England.
The Brazilian FA are leading the South American nations taking revenge for clubs blocking their players from travelling to 'red-list' countries, by imposing a 'five-day restriction' on the players they called up, even though they did not fly.
The news means Liverpool are set to be without Brazilian trio Alisson, Fabinho and Roberto Firmino for their clash at Leeds on Sunday, while Raphinha will be missing for the home side.