Pep Guardiola fears leading managers are powerless to stop an injury crisis this season as he prepares to face Leicester City on Sunday without a senior striker.
Guardiola, already without record scorer Sergio Aguero, will also miss Gabriel Jesus for City's next three games at least after he suffered muscular problems during the win at Wolves on Monday.
Raheem Sterling may be forced to play a false nine on Sunday afternoon while 17-year-old Liam Delap should be on the bench following his debut goal against Bournemouth in the EFL Cup.