Manchester City can extend their winning run to 22 games should they record a victory over bitter rivals United in the big derby on Sunday evening.
Pep Guardiola's men look to be cruising to the Premier League title and will take a huge step closer to regaining the crown with three points over Ole Gunnar Solskjaer's side - stretching their lead to 15 points.
United are second in the table and have slipped away from the title conversation after a string of 0-0 draws and uninspiring displays. They have a poor record against the big six this season but will be hopeful of at least ending City's winning streak.