Napoli president Aurelio De Laurentiis would like to see some key players rested against Manchester City in the Champions League on Tuesday.
The current Serie A leaders face a top-of-the-table clash with Inter on Saturday, who are fresh from a stoppage-time victory over bitter rivals AC on Sunday evening.
Inter closed the gap to the league leaders to just two points after their 3-2 victory at a capacity San Siro just one day after Napoli gained some breathing space with a well-earned victory at Roma.
'Those players that have been compiling a lot of minutes should be rested a bit in this match to keep them fresh,' De Laurentiis said.