Claudio Bravo endured a nightmare return to Catalonia as his sending off opened the floodgates for Barcelona to run riot against Manchester City.
Bravo saw red early on in the second half for a deliberate handball outside his penalty area from a Luis Suarez shot.
His dismissal was with the scoreline at 1-0 thanks to a Lionel Messi strike, but the latter quickly completed his hat-trick afterwards.
Jeremy Mathieu also saw red for Barcelona but they managed to add a fourth goal through Neymar despite him missing a penalty too.
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