Fansided · Oct 18, 2025
No. 10 LSU vs No. 17 Vanderbilt: Final odds and score prediction
South Carolina v LSU | Michael DeMocker/GettyImagesThe LSU Tigers have won 10 straight matchups against the Vanderbilt Commodores going back to 1991. LSU owns the all-time series lead against Vanderbilt 25-7-1, and Vandy has just one win over LSU since 1960. But these aren't the same old Commodores. Clark Lea has turned the program around and has his team with a 5-1 record and No. 17 ranking heading into this weekend.
As kick-off for Week 8's highly-anticipated matchup between the Tigers and Commodores draws nearer, here are the latest LSU vs Vanderbilt betting odds, as well as a score prediction for the game.
LSU vs Vanderbilt betting odds