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LSU vs South Carolina early betting odds: Can LSU bounce back?

After suffering their first loss of the 2025 season against Ole Miss, the LSU Tigers got a much-needed bye week in Week 6. The underwhelming play of the LSU offense and the healthy of Garrett Nussmeier remain the two main talking points surrounding the Tigers' bye week. South Carolina is also coming off a bye week, so both the Tigers and Gamecocks have had ample time to rest up and prepare for this matchup.

LSU has dominated the all-time series against South Carolina, claiming a record of 20-2-1 against the Gamecocks. LSU has won nine consecutive meetings since 1995, and won by a score of 36-33 in Columbia last season.