Sportsbooks have LSU as a 13.5-point favorite against Ole Miss for Saturday's game (Sept. 29) in Tiger Stadium.
Some books have the line down to 13 already. Eighty percent of bets are on LSU as of Monday morning, according to SportsInsights. LSU is 2-2 against the spread this season.
LSU won last year's meeting 40-24, and this season LSU is 4-0 and ranked No. 5 in the Associated Press Poll.
Ole Miss is 3-1 with a win against No. 25 Texas Tech, but the Rebels were also beat 62-7 by Alabama.