Week 16 in the NFL started on Christmas Day with a huge performance by the New Orleans Saints and Alvin Kamara, who became the second running back in league history to rush for six touchdowns in a game. The Saints also clinched the NFC South with a victory over the Minnesota Vikings.
On Saturday, the Tampa Bay Buccaneers handed the Detroit Lions a lopsided loss while clinching a playoff spot for the first time since 2005.Then, the San Francisco 49ers upset the Arizona Cardinals, who lost control of their own playoff destiny.