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Louisville vs Boston College early odds and a prediction

Louisville football is coming off one of its biggest wins in program history after the Cardinals completely stunned the No. 2 team in the country and the ACC frontrunner in the Miami Hurricanes. Louisville played its best game in the biggest opportunity and showed its full potential in the 24-21 win.

Now, the Cardinals are ranked No. 19 in the nation and are right back in the ACC race. The Cards are 5-1 on the season and 3-1 in the ACC. Louisville has a track record of winning big games under head coach Jeff Brohm, as the Cardinals defeated Notre Dame and Clemson in his first two seasons, but they also have a record of a letdown game after their big win.